An ILP solution for the gene duplication problem

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چکیده

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The multiple gene duplication problem revisited

MOTIVATION Deciphering the location of gene duplications and multiple gene duplication episodes on the Tree of Life is fundamental to understanding the way gene families and genomes evolve. The multiple gene duplication problem provides a framework for placing gene duplication events onto nodes of a given species tree, and detecting episodes of multiple gene duplication. One version of the mult...

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On the Multiple Gene Duplication Problem

A fundamental problem in computational biology is the determination of the correct species tree for a set of taxa given a set of (possibly contradictory) gene trees. In recent literature, the Duplication/ Loss model has received considerable attention. Here one measures the similarity/dissimilarity between a set of gene trees by counting the number of paralogous gene duplications and subsequent...

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ژورنال

عنوان ژورنال: BMC Bioinformatics

سال: 2011

ISSN: 1471-2105

DOI: 10.1186/1471-2105-12-s1-s14